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Ulrich Herrlinger Selected Research

Lomustine (CCNU)

8/2022Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS.
1/2022Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy-the MecMeth/NOA-24 trial.
2/2021Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status.
1/2021MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
1/2021Diagnosis of Pseudoprogression Following Lomustine-Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET.
5/2020Neurocognitive functioning and health-related quality of life in adult medulloblastoma patients: long-term outcomes of the NOA-07 study.
3/2020Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma.
1/2020Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling.
10/2019Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
1/2019Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
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Ulrich Herrlinger Research Topics

Disease

63Glioblastoma (Glioblastoma Multiforme)
08/2022 - 10/2002
41Neoplasms (Cancer)
06/2022 - 02/2002
27Glioma (Gliomas)
11/2022 - 01/2004
11Lymphoma (Lymphomas)
12/2020 - 02/2002
8Brain Neoplasms (Brain Tumor)
06/2022 - 01/2016
6Astrocytoma (Pilocytic Astrocytoma)
01/2022 - 10/2002
5Meningioma (Meningiomas)
03/2022 - 08/2011
4Medulloblastoma
05/2020 - 03/2005
3Neoplasm Metastasis (Metastasis)
03/2022 - 08/2004
3Disease Progression
01/2019 - 12/2010
3Neuroepithelial Neoplasms (Gliomatosis Cerebri)
09/2011 - 10/2002
2Thrombocytopenia (Thrombopenia)
01/2022 - 09/2014
2Multiple Sclerosis
04/2021 - 03/2016
2Hemorrhage
01/2021 - 08/2003
2Infections
01/2021 - 10/2008
2Melanoma (Melanoma, Malignant)
10/2016 - 06/2013
2Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2010 - 08/2009
1Obesity
08/2022
1Inflammation (Inflammations)
01/2022
1Cytopenia
01/2022
1Acoustic Neuroma (Acoustic Neurinoma)
01/2022
1Ependymoma
08/2021
1Edema (Dropsy)
07/2021
1Iatrogenic Disease
10/2020
1Urinary Tract Infections (Urinary Tract Infection)
09/2020
1Postoperative Hemorrhage
09/2020
1Nausea
01/2020
1Cognitive Dysfunction
01/2020
1Death (Near-Death Experience)
01/2020
1Vomiting
01/2020
1Aseptic Meningitis
12/2019
1Myofibromatosis
01/2019

Drug/Important Bio-Agent (IBA)

31Temozolomide (Temodar)FDA LinkGeneric
11/2022 - 09/2006
15Lomustine (CCNU)FDA Link
08/2022 - 09/2006
11Bevacizumab (Avastin)FDA Link
08/2022 - 01/2013
8Tyrosine (L-Tyrosine)FDA Link
04/2021 - 04/2015
8MethyltransferasesIBA
02/2021 - 09/2006
8Methotrexate (Mexate)FDA LinkGeneric
12/2020 - 02/2002
7Irinotecan (Camptosar)FDA LinkGeneric
08/2022 - 01/2013
5Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
11/2022 - 02/2016
4Pharmaceutical PreparationsIBA
01/2022 - 06/2013
4C-Reactive ProteinIBA
01/2022 - 12/2020
4Procarbazine (Matulane)FDA Link
01/2020 - 10/2002
4DNA (Deoxyribonucleic Acid)IBA
04/2017 - 08/2007
3Amino AcidsFDA Link
06/2022 - 04/2015
3Fibrinogen (Factor I)FDA Link
03/2022 - 01/2021
3Biomarkers (Surrogate Marker)IBA
01/2021 - 05/2015
3Vincristine (Oncovin)FDA LinkGeneric
05/2020 - 10/2002
3(18F)fluoroethyltyrosineIBA
07/2018 - 03/2016
3O(6)-Methylguanine-DNA MethyltransferaseIBA
10/2016 - 03/2009
3Phosphotransferases (Kinase)IBA
01/2014 - 11/2004
2Proteins (Proteins, Gene)FDA Link
06/2022 - 02/2016
2Meclofenamic Acid (Meclofenamate)FDA LinkGeneric
01/2022 - 11/2021
2Indicators and Reagents (Reagents)IBA
01/2021 - 01/2019
2Cytarabine (Cytosar-U)FDA LinkGeneric
12/2020 - 02/2010
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2020 - 02/2016
2Angiopoietin-2IBA
12/2019 - 01/2016
2CytokinesIBA
12/2019 - 11/2004
2regorafenibIBA
12/2019 - 11/2019
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2019 - 01/2013
2O-(6)-methylguanineIBA
04/2017 - 08/2007
2Carmustine (FIVB)FDA Link
01/2014 - 10/2002
1SteroidsIBA
08/2022
1gamma-glutamylaminomethylsulfonic acid (GAMS)IBA
06/2022
1Levetiracetam (Keppra)FDA LinkGeneric
04/2022
1AcidsIBA
04/2022
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2022
1Acute-Phase Proteins (Acute-Phase Protein)IBA
02/2022
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2022
1Ion Channels (Ion Channel)IBA
02/2021
1phenyl-2-aminoethyl sulfide (PAES)IBA
10/2020
1MicroRNAs (MicroRNA)IBA
09/2020
1Cisplatin (Platino)FDA LinkGeneric
05/2020
1Alkylating AgentsIBA
03/2020
1Adrenal Cortex Hormones (Corticosteroids)IBA
12/2019
1dimemorfan (AT 17)IBA
10/2019
1Imatinib Mesylate (Gleevec)FDA Link
01/2019
1Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
01/2019
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2019
1dabrafenibIBA
12/2017
1Contrast MediaIBA
08/2017
1GadoliniumIBA
08/2017

Therapy/Procedure

35Therapeutics
06/2022 - 02/2002
24Drug Therapy (Chemotherapy)
11/2022 - 10/2002
24Radiotherapy
08/2022 - 02/2002
13Chemoradiotherapy
01/2022 - 07/2010
3Anterior Temporal Lobectomy
04/2021 - 10/2019
3Artificial Respiration (Mechanical Ventilation)
01/2021 - 01/2020
3Aftercare (After-Treatment)
01/2020 - 01/2008
3Combination Drug Therapy (Combination Chemotherapy)
01/2018 - 02/2010
2Re-Irradiation
01/2022 - 04/2014
2Maintenance Chemotherapy
05/2020 - 04/2017
2Palliative Care (Palliative Therapy)
01/2020 - 12/2014
1Blood Transfusion (Blood Transfusions)
04/2022
1Erythrocyte Transfusion
04/2022
1Precision Medicine
09/2021
1Conformal Radiotherapy
01/2021
1Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
01/2021
1Immunomodulation
01/2021
1Catheters
09/2020